Copic markers are available in 358 permanent, non-toxic, alcohol-based ink colors and are refillable using standard color ink refills. The refill inks can be mixed to create custom colors, and empty markers are sold for this purpose. The markers are airtight to prevent them from drying out and they are guaranteed a shelf-life of 3 years. Sketch markers, which are the most popular version, have a chisel-style tip at one end and a brush tip at the other, though additional styles of replaceable nibs and tips are available.

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